Hypertriglyceridemia in Gout.

THE incidence of arteriosclerosis is reported to be greater in patients with gout than in control groups. In one study of 280 individuals with gout, 39 per cent had clinical or electrocardiographic evidence -of cardiovascular disease and 45 per cent had hypertension.' Severe involvement of the coronary or cerebral vessels and marked renal arteriosclerosis are major factors in producing death in patients with gout.2 Conversely, hyperuricemia is more frequent in patients with essential hypercholesteremia 3 or with coronary artery disease 5 6 than in normal persons. The mechanism underlying these relationships is obscure. There has been recent emphasis on the association of hypertriglyceridemia and coronary heart disease.7 The present study was performed to evaluate the relation between the levels of circulating triglycerides and other complex lipids in patients with gout in comparison to an appropriate control group.